Merck initiates phase 3 study for dengue vaccine in children

Published 12/06/2025, 12:02
© Reuters.

Investing.com -- Merck & Co Inc (NYSE:MRK) has started a Phase 3 clinical trial to evaluate its dengue vaccine candidate, the pharmaceutical company announced Thursday.

The study will enroll approximately 12,000 individuals between the ages of 2 and 17 years. Researchers will assess a single dose of V181 for the prevention of dengue caused by any of the four serotypes of the virus, regardless of previous exposure.

This large-scale trial represents a significant step in Merck (NSE:PROR)’s development program for the dengue vaccine candidate as it moves into the final stage of clinical testing before potential regulatory submission.

Dengue fever is a mosquito-borne viral disease that affects millions of people globally each year, with children being particularly vulnerable to severe forms of the illness.

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