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This article summarizes the top insider buys and sells for US stocks reported on Thursday, October 23, 2025.
Top Insider Buys:
Summit Therapeutics Inc. (NASDAQ:SMMT) saw significant insider buying activity. Director Xia Yu acquired 533,617 shares at $18.74 per share, totaling approximately $9.9 million. The purchase was made through a private placement transaction. Following this acquisition, Xia Yu now indirectly owns 32,057,147 shares through Akeso, Inc.
Neuphoria Therapeutics Inc. (NASDAQ:NEUP) reported a substantial purchase by Lynx1 Capital Management LP, a ten percent owner. The firm bought 639,110 shares at prices ranging from $4.96 to $5.20, with an average price of $5.137, totaling $3,283,108. This acquisition comes despite recent setbacks in the company’s clinical trials and a strategic review of operations.
Summit Therapeutics Inc. (NASDAQ:SMMT) also saw buying activity from Robert W. Duggan, a director and Co-Chief Executive Officer. Duggan acquired 26,680 shares at $18.74 per share, valued at $499,983. Additionally, he purchased 14,247,597 shares through private placement transactions, totaling approximately $266,999,967.
Director Mahkam Zanganeh of Summit Therapeutics Inc. (NASDAQ:SMMT) joined the buying trend, purchasing 26,680 shares at $18.74 per share, for a total of $499,983. Zanganeh also acquired 14,274,405 shares through private placement transactions at the same price.
ASA Gold & Precious Metals Ltd (NYSE:ASA) saw Saba Capital Management, L.P., a ten-percent owner, purchase a total of 45,090 shares in two transactions. The firm bought 24,550 shares at $45.2 each on October 21, and an additional 20,540 shares at $44.77 each on October 22, for a total value of $2,029,235.
Top Insider Sells:
Nvidia (NASDAQ:NVDA) reported a significant sale by President and CEO Huang Jen Hsun. He sold 201,221 shares between October 21 and October 23, 2025, for approximately $40.7 million, at prices ranging from $177.5699 to $183.2697.
InnsSuites Hospitality Trust (NASDAQ:IHT) saw President and CEO James F. Wirth sell 10,000 shares at $14,507.0 per share, totaling $145,070,000.
Samsara Inc (NYSE:IOT) reported sales by CEO Sanjit Biswas, who sold a total of 158,691 shares of Class A Common Stock in multiple transactions, for a combined value of approximately $6.18 million.
Director John Bicket of Samsara Inc (NYSE:IOT) also sold shares, disposing of 169,680 shares of Class A Common Stock in multiple transactions, for a total value of approximately $6.57 million.
Asana, Inc. (NASDAQ:ASAN) Director Justin Rosenstein sold 458,878 shares of Class A Common Stock for approximately $6.87 million, at prices ranging from $14.95 to $15.07.
Investors should stay tuned to insider buying and selling activities as they can provide valuable insights into a company’s prospects. While insider transactions alone should not be the basis for investment decisions, they can offer clues about management’s confidence in the company’s future performance or potential concerns. It’s important to consider these moves alongside other fundamental and technical analysis when evaluating investment opportunities.
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