Praxis Precision Medicines exec sells $2.6m in shares

Published 22/11/2025, 03:46
Praxis Precision Medicines exec sells $2.6m in shares

Lauren Mastrocola, Principal Accounting Officer at Praxis Precision Medicines, Inc. (NASDAQ:PRAX), sold 13,600 shares of common stock on November 20, 2025, for approximately $2.6 million. The sales were executed in multiple transactions with prices ranging from $191.958 to $192.711.

On the same day, Mastrocola also exercised options to acquire 13,100 shares of Praxis Precision Medicines common stock at prices ranging from $43.37 to $133.65, for a total value of $831257.

In other recent news, Praxis Precision Medicines announced a public offering of 3,025,480 shares of common stock priced at $157.00 per share, along with pre-funded warrants to purchase up to 318,470 shares. This offering is expected to generate approximately $525 million. Guggenheim has raised its price target for Praxis Precision Medicines to $540.00, maintaining a Buy rating due to progress in the company’s central nervous system drug candidates. The firm anticipates a potential FDA meeting later this year to discuss an NDA filing for ulixacaltamide, which could represent a significant sales opportunity.

Praxis has also reached alignment with the FDA on key aspects of its relutrigine development program for treating rare epilepsies, with plans for a New Drug Application submission in early 2026 if interim study results are positive. However, a recent short report from Culper Research has questioned the company’s Phase 3 trial results for its essential tremor treatment, alleging methodological changes and over-optimistic results. Despite these challenges, the company’s developments continue to attract attention from analysts and investors.

This article was generated with the support of AI and reviewed by an editor. For more information see our T&C.

Latest comments

Risk Disclosure: Trading in financial instruments and/or cryptocurrencies involves high risks including the risk of losing some, or all, of your investment amount, and may not be suitable for all investors. Prices of cryptocurrencies are extremely volatile and may be affected by external factors such as financial, regulatory or political events. Trading on margin increases the financial risks.
Before deciding to trade in financial instrument or cryptocurrencies you should be fully informed of the risks and costs associated with trading the financial markets, carefully consider your investment objectives, level of experience, and risk appetite, and seek professional advice where needed.
Fusion Media would like to remind you that the data contained in this website is not necessarily real-time nor accurate. The data and prices on the website are not necessarily provided by any market or exchange, but may be provided by market makers, and so prices may not be accurate and may differ from the actual price at any given market, meaning prices are indicative and not appropriate for trading purposes. Fusion Media and any provider of the data contained in this website will not accept liability for any loss or damage as a result of your trading, or your reliance on the information contained within this website.
It is prohibited to use, store, reproduce, display, modify, transmit or distribute the data contained in this website without the explicit prior written permission of Fusion Media and/or the data provider. All intellectual property rights are reserved by the providers and/or the exchange providing the data contained in this website.
Fusion Media may be compensated by the advertisers that appear on the website, based on your interaction with the advertisements or advertisers
© 2007-2025 - Fusion Media Limited. All Rights Reserved.