Praxis Precision Medicines, Inc., a clinical-stage biopharmaceutical company, engages in the development of therapies for central nervous system (CNS) disorders characterized by neuronal excitation-inhibition imbalance. The company’s platforms include cerebrum, a small molecule platform for CNS small molecule therapies to develop orally available precision therapies; and solidus to discover and develop antisense oligonucleotide. It also develops Ulixacaltamide, a small molecule inhibitor of T-type calcium channels that is in Phase 3 clinical trial for the treatment of essential tremor; Vormatrigine, a small molecule targeting the hyperexcitable state of sodium-channels in the brain to treat focal onset epilepsy; Relutrigine for the treatment of developmental and epileptic encephalopathies; PRAX-020 to treat KCNT1; and PRAX-050. In addition, the company develops Elsunersen, a clinical-stage ASO designed to regulate NaV1.2 expression for the treatment of SCN2A-DEE; PRAX-080 that targets PCDH19-related developmental epilepsy; PRAX-090 for targeting SYNGAP1 loss-of-function; and PRAX-100 that targets SCN2A LoF mutations. It has a license agreement with RogCon Inc.; and research collaboration and license agreement with Ionis Pharmaceuticals, Inc. Praxis Precision Medicines, Inc. was incorporated in 2015 and is based in Boston, Massachusetts.
Metrics to compare | PRAX | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipPRAXPeersSector | |
---|---|---|---|---|
P/E Ratio | −4.6x | −3.5x | −0.7x | |
PEG Ratio | 0.17 | 0.09 | 0.00 | |
Price/Book | 2.8x | 1.7x | 2.6x | |
Price / LTM Sales | 147.2x | 10.6x | 3.4x | |
Upside (Analyst Target) | 50.1% | 174.1% | 35.7% | |
Fair Value Upside | Unlock | 8.4% | 4.1% | Unlock |