UPDATE 2-London's FTSE 100 gives in to fears over U.S.-Iran tensions

* FTSE 100 down 0.2%, FTSE 250 down 0.3%
* IQE drops as Huawei curbs hit revenue
* U.S.-Iran tensions weigh
* Domino's Pizza drops among midcaps

(Adds company news items, updates share moves)
By Muvija M
June 21 (Reuters) - Britain's main stock index handed back
gains on Friday as rises in oil majors driven by the potential
for supply disruptions due to tensions in the Middle East were
not enough to offset general gloom about a threatened U.S.-Iran
military standoff.
The FTSE 100 .FTSE edged 0.2% lower, with losses spread
across most sectors, and the FTSE 250 midcap index .FTMC was
down 0.4%.
The oil and gas sector was a bright spot, with heavyweights
Shell RDSa.L and BP BP.L gaining on the back of a jump in
crude prices after a report that U.S. President Donald Trump had
approved military strikes against Iran then pulled them back.

"Overtones of the trade conflict are, like the unseasonably
wet weather in much of Europe right now, difficult to avoid and
likely to put a dampener on things," City Index analyst Ken
Odeluga said.
"The simmering and increasingly unpredictable U.S.-Iran
stand-off has also chilled the week's revived cheer."
After a solid run during a week in which the U.S. Federal
Reserve and the European Central Bank signalled more stimulus if
the economy weakens, there seemed to be some profit taking in
markets, CMC Markets analyst David Madden said.
The gains from the earlier in the week have placed the FTSE
100 on course for its best month since January, after it
suffered its first monthly fall in May this year due to
escalations in the U.S.-China trade war.
Keeping in mind the upcoming meeting between Presidents
Donald Trump and Xi Jinping next week at the G-20 summit, Madden
said there could be some more profit-taking ahead.
IQE Plc IQE.L , which makes semiconductor wafers for chips,
slumped 24.8% on its worst day since November after warning
annual revenue would be lower than expected because U.S.
restrictions on China's Huawei HWT.UL are affecting orders.
The alert dragged down European peers, and came after U.S.
chipmaker Broadcom AVGO.O rattled the industry with a forecast
that U.S.-China trade tensions and the curbs on Huawei would
wipe $2 billion off its sales this year. Another semiconductor firm, Nanoco NANON.L , plummeted 74%,
its biggest one-day drop on record, after it said a U.S.
customer had informed it that its project with the company will
not continue beyond their current contract.
Among midcaps, Domino's Pizza Group DOM.L fell 3.7% after
a frontrunner to replace its outgoing chief executive slapped
down a media report that he would step into the role. Andrew
Rennie insisted he was invested in his job as European head of
Domino's Pizza Enterprises DMP.AX .