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Olema Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of therapies for women’s cancers. The company’s lead product candidate is palazestrant, an estrogen receptor (ER) antagonist and a selective ER degrader, which is in Phase 3 clinical trial for the treatment of recurrent, locally advanced, or metastatic estrogen receptor-positive, human epidermal growth factor receptor 2-negative breast cancer; OPERA-01, the pivotal Phase 3 clinical trial of palazestrant as a monotherapy in second/third-line ER+/HER2- metastatic breast cancer; and palazestrant with CDK4/6 inhibitors palbociclib and ribociclib, a phosphatidylinositol 3 kinase alpha (PI3Ka) inhibitor alpelisib, and with an mTOR inhibitor everolimus that is in Phase 1/2 clinical trial for the treatment of recurrent, locally advanced, or metastatic estrogen receptor-positive human epidermal growth factor receptor 2-negative breast cancer. It also develops OP-3136, an orally-available small molecule that potently and selectively inhibits KAT6 for patients with ER+/HER2- metastatic breast cancer and other cancers which is in Phase 1 clinical trial. The company was formerly known as CombiThera, Inc. and changed its name to Olema Pharmaceuticals, Inc. in March 2009. Olema Pharmaceuticals, Inc. was incorporated in 2006 and is headquartered in San Francisco, California.
Name | Age | Since | Title |
---|---|---|---|
Graham L. Gordon Walmsley | 37 | 2020 | Independent Director |
Cynthia Marie Butitta | 70 | 2020 | Independent Director |
Andrew S. Rappaport | 65 | 2013 | Independent Director |
Sean P. Bohen | 57 | 2020 | President, CEO & Director |
Ian T. Clark | 64 | 2020 | Independent Chairperson of the Board |
Cyrus L. Harmon | 53 | 2006 | Director |
Pamela M. Klein | 63 | 2020 | Member of Scientific Advisory Board |
Jeffrey Hager | 59 | - | Member of Scientific Advisory Board |
Yi Larson | 43 | 2021 | Independent Director |
Geoffrey Greene | - | - | Member of Scientific Advisory Board |
Gorjan Hrustanovic | 35 | 2018 | Independent Director |
Frank P. McCormick | 74 | 2014 | Chairman of Scientific Advisory Board |
Sandra J. Horning | 75 | 2020 | Independent Director |
Sean W. Fanning | - | - | Member of Scientific Advisory Board |
Mark Sliwkowski | - | - | Member of Scientific Advisory Board |
Christopher C. Benz | - | - | Member of Scientific Advisory Board |
Scott Garland | 55 | 2023 | Independent Director |
Pamela N. Munster | - | - | Member of Scientific Advisory Board |
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