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iTeos Therapeutics, Inc., a clinical-stage biopharmaceutical company, engages in the discovery and development of immuno-oncology therapeutics for patients with cancer. The company’s lead antibody product candidate, belrestotug, an antagonist of T-cell immunoreceptor with Ig and ITIM domains (TIGIT), as well as engages the Fc gamma receptor to activate dendritic cells, natural killer cells, T lymphocytes, and macrophages and to promote the release of cytotoxic granules and antibody-dependent cellular cytotoxicity activity. Its product pipeline also includes inupadenant, a next-generation A2AR antagonist program; EOS-984, a small molecule targeting equilibrative nucleoside transporter 1 (ENT1) to reverse immunosuppression and restore T cell proliferation in the tumor microenvironment; and EOS-215, a monoclonal antibody which antagonizes triggering receptor expressed on triggering receptor expressed on myeloid cells 2. Iteos Therapeutics, Inc. was founded in 2011 and is headquartered in Watertown, Massachusetts.
Name | Age | Since | Title |
---|---|---|---|
Michel Detheux | 58 | 2011 | President, CEO & Director |
David L. Hallal | 59 | 2018 | Independent Chairman of the Board |
Gordon Freeman | - | - | Chairman of Scientific Advisory Board |
Ann D. Rhoads | 60 | 2020 | Independent Director |
Robert Iannone | 58 | 2021 | Independent Director |
Roberta Zappasodi | - | - | Member of Scientific Advisory Board |
Florent Ginhoux | - | - | Member of Scientific Advisory Board |
Benoit Van den Eynde | - | - | Member of Scientific Advisory Board |
Matthew Vander Heiden | - | - | Member of Scientific Advisory Board |
Mark Chao | - | - | Member of Scientific Advisory Board |
David K. Lee | 43 | 2023 | Independent Director |
Tony W. Ho | 59 | 2021 | Independent Director |
Jill M. DeSimone | 69 | 2024 | Independent Director |
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