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Actinium Pharmaceuticals, Inc. develops antibody radiation conjugates and other targeted radiotherapies intended to improve outcomes for people who have failed existing oncology therapies. The company advances two clinical stage product candidates, Actimab-A, to treat patients with myeloid malignancies including acute myeloid leukemia and myelodysplastic syndromes; and Iomab-ACT, to improve patient access to and outcomes with cellular therapies, such as CAR-T for various blood cancer indications and gene therapies for non-malignant hematologic disorders such as sickle cell disease. It also develops ATNM-400, a preclinical non-prostate specific-membrane antigen targeting radiotherapy utilizing the Actinium-225 radioisotope for patients with prostate cancer. In addition, the company's Iomab-B is an induction and conditioning agent prior to bone marrow transplant in patients with relapsed and refractory acute myeloid leukemia (r/r AML). Further, it engages with the National Cancer Institute under the cooperative research and development agreement for the development of Actimab-A in AML and other myeloid malignancies, and its research and development activities primarily focus on advancing various preclinical programs for solid tumor indications. The company is based in New York, New York.
Name | Age | Since | Title |
---|---|---|---|
Elihu H. Estey | - | - | Member of Clinical Advisory Board |
Sandesh C. Seth | 60 | 2012 | Chairman & CEO |
Sergio Giralt | - | 2014 | Member of Scientific Advisory Board |
David A. Scheinberg | 68 | - | Member of Clinical Advisory Board |
Franklin Wong | - | 2018 | Members of Nuclear Medicine Clinical Advisory Board |
Hagop M. Kantarjian | - | - | Member of Clinical Advisory Board |
Jeffrey W. Chell | 70 | 2018 | Independent Director |
Johannes Czernin | - | 2018 | Members of Nuclear Medicine Clinical Advisory Board |
Alexander Perl | - | - | Member of Clinical Advisory Board |
Hillard M. Lazarus | - | 2014 | Member of Scientific Advisory Board |
C. David Nicholson | 69 | 2008 | Lead Independent Director |
Richard E. Champlin | - | 2014 | Member of Scientific Advisory Board |
Michael Yu | - | 2018 | Members of Nuclear Medicine Clinical Advisory Board |
Dan Pryma | - | 2018 | Members of Nuclear Medicine Clinical Advisory Board |
Ajit S. Shetty | 77 | 2017 | Independent Director |
John M. Pagel | - | - | Chairman of Scientific Advisory Board & Member of Clinical Advisory Board |
Richard L. Wahl | - | - | Member of Clinical Advisory Board |
Joseph G. Jurcic | - | - | Chairman of Clinical Advisory Board |
Richard M. Stone | - | 2017 | Member of Scientific Advisory Board |
M. Yair Levy | - | 2014 | Member of Scientific Advisory Board |
Richard I. Steinhart | 67 | 2013 | Independent Director |
Ghassan El-Haddad | - | 2018 | Members of Nuclear Medicine Clinical Advisory Board |
June S. Almenoff | 68 | 2024 | Independent Director |
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