Taysha Gene Therapies, Inc., a clinical-stage biotechnology company, focuses on developing and commercializing adeno-associated virus-based gene therapies for the treatment of monogenic diseases of the central nervous system. It primarily develops TSHA-120 for the treatment of giant axonal neuropathy; TSHA-102 for the treatment of Rett syndrome; TSHA-121 for the treatment of CLN7 disease; TSHA-118 for the treatment of CLN1 disease; TSHA-105 for the treatment of SLC13A5 deficiency; TSHA-113 for the treatment of tauopathies; TSHA-106 for the treatment of angelman syndrome; TSHA-114 for the treatment of fragile X syndrome; and TSHA-101 for the treatment of GM2 gangliosidosis. The company has research, collaboration, and license agreement with The University of Texas Southwestern Medical Center. Taysha Gene Therapies, Inc. was incorporated in 2019 and is headquartered in Dallas, Texas.
Gene Therapy Promise | Taysha's TSHA-102 shows potential in treating Rett syndrome, with positive preliminary data and strategic clinical trial advancements boosting investor confidence |
Financial Fortification | Recent $76.8M offering extends cash runway to Q4 2026, strengthening Taysha's position to fund ongoing trials and operational expenses without immediate financial pressure |
Regulatory Roadmap | RMAT designation and upcoming regulatory meetings could expedite TSHA-102's approval process, with key milestones expected to provide clarity on the path to market |
Market Opportunity | Analysts set price targets ranging from $5 to $8 per share, reflecting optimism about Taysha's potential in the estimated $2 billion+ Rett syndrome treatment market |
Metrics to compare | TSHA | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipTSHAPeersSector | |
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P/E Ratio | −6.7x | −1.0x | −0.5x | |
PEG Ratio | −0.12 | −0.05 | 0.00 | |
Price/Book | 10.6x | 2.2x | 2.6x | |
Price / LTM Sales | 80.8x | 8.9x | 3.3x | |
Upside (Analyst Target) | 194.1% | 318.8% | 43.5% | |
Fair Value Upside | Unlock | 7.6% | 6.8% | Unlock |