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Xilio Therapeutics, Inc., a clinical-stage biotechnology company, engages in the discovery and development of tumor-activated immuno-oncology therapies. The company’s checkpoint inhibitor program includes XTX101, an investigational Fc-enhanced, tumor-activated anti-CTLA-4 mAb that is in Phase 2 clinical trial for patients with advanced solid tumors. It also develops cytokine programs, which comprises XTX202, a tumor-activated beta-gamma biased IL-2, currently under Phase 2 clinal trials; and XTX301, an investigational tumor-activated, engineered IL-12 molecule, currently under Phase 1 studies. The company was founded in 2016 and is headquartered in Waltham, Massachusetts.
| Name | Age | Since | Title |
|---|---|---|---|
| Jason J. Luke | - | 2021 | Member of Scientific Advisory Board |
| Robert Ross | - | - | Director |
| Paul J. Clancy | 63 | 2020 | Non-Employee Independent Chairman |
| Christina Rossi | 49 | 2021 | Independent Director |
| Rene Russo | 50 | 2019 | President, CEO & Director |
| Daniel Curran | 58 | 2020 | Independent Director |
| Sara M. Bonstein | 44 | 2021 | Independent Director |
| Yuan Xu | 57 | 2022 | Independent Director |
| Robert W. Ross | 51 | 2022 | Independent Director |
| Akintunde Bello | - | 2025 | Director |
| Aoife M. Brennan | 49 | 2024 | Independent Director |
| James S. Shannon | 69 | 2024 | Independent Director |
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