Spyre Therapeutics Inc (SYRE)

Currency in USD
15.240
-0.720(-4.51%)
Closed·
After Hours
15.2400.000(0.00%)
·
SYRE Scorecard
Full Analysis
Holds more cash than debt on its balance sheet
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Fair Value
Day's Range
14.93515.900
52 wk Range
10.91040.260
Key Statistics
Prev. Close
15.96
Open
15.9
Day's Range
14.935-15.9
52 wk Range
10.91-40.26
Volume
332.48K
Average Volume (3m)
570.52K
1-Year Change
-38.71%
Book Value / Share
5.42
Fair Value
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Fair Value Upside
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SYRE Scorecardpro icon
Company’s Health
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Fair Value
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Fair Price
Upside
Price Target
54.889
Upside
+260.16%
Members' Sentiments
Bearish
Bullish
ProTips
3 analysts have revised their earnings upwards for the upcoming period

Spyre Therapeutics Inc News & Analysis

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Technical Analysis

Summary
Strong Sell
Sell
Neutral
Buy
Strong Buy
Strong Sell
Technical Indicators
Strong Sell
Moving Averages
Sell

Spyre Therapeutics Inc Company Profile

Spyre Therapeutics, Inc., a clinical stage biotechnology company, focuses on developing therapeutics for patients living with inflammatory bowel disease (IBD). It develops SPY001, a human monoclonal immunoglobulin G1 antibody designed to bind selectively to the a4ß7 integrin being developed for the treatment of IBD (ulcerative colitis and Crohn’s disease). The company is developing SPY002, a human monoclonal antibody (mAb)candidates designed to bind to tumor necrosis factor-like ligand 1A; and SPY120, a combination of SPY001 (anti-a4ß7) and SPY002 (anti-TL1A) antibodies, which are in preclinical studies. In addition, its other early-stage programs include SPY003, an anti-IL-23 mAb; SPY004; SPY130, a combination of anti-a4ß7 and anti-IL-23 mAbs; and SPY230, a combination of anti-TL1A and anti-IL-23 mAbs. The company was formerly known as Aeglea BioTherapeutics, Inc. and changed its name to Spyre Therapeutics, Inc. in November 2023. The company was incorporated in 2013 and is based in Waltham, Massachusetts.

Compare SYRE to Peers and Sector

Metrics to compare
SYRE
Peers
Sector
Relationship
P/E Ratio
−5.7x−3.1x−0.5x
PEG Ratio
−0.110.000.00
Price/Book
3.1x2.2x2.6x
Price / LTM Sales
-9.2x3.3x
Upside (Analyst Target)
307.3%210.8%43.5%
Fair Value Upside
Unlock11.0%6.9%Unlock

Analyst Ratings

11 Buy
1 Hold
0 Sell
Ratings:
12 analysts
Overall Consensus
Strong Buy

Analysts 12-Month Price Target:

Average 54.889
(+260.16% Upside)

Earnings

Latest Release
Aug 05, 2025
EPS / Forecast
-0.49 / -0.7538
Revenue / Forecast
-- / --
EPS Revisions
Last 90 days

SYRE Income Statement

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FAQ

What Stock Exchange Does Spyre Therapeutics Trade On?

Spyre Therapeutics is listed and trades on the Nasdaq Stock Exchange stock exchange.

What Is the Stock Symbol for Spyre Therapeutics?

The stock symbol for Spyre Therapeutics is "SYRE."

What Is the Spyre Therapeutics Market Cap?

As of today, Spyre Therapeutics market cap is 909.64M.

What Is Spyre Therapeutics's Earnings Per Share (TTM)?

The Spyre Therapeutics EPS (TTM) is -3.01.

When Is the Next Spyre Therapeutics Earnings Date?

Spyre Therapeutics will release its next earnings report on 05 Nov 2025.

From a Technical Analysis Perspective, Is SYRE a Buy or Sell?

Based on moving averages and other technical indicators, the daily buy/sell signal is Strong Sell.

How Many Times Has Spyre Therapeutics Stock Split?

Spyre Therapeutics has split 1 times.

How Many Employees Does Spyre Therapeutics Have?

Spyre Therapeutics has 87 employees.

What is the current trading status of Spyre Therapeutics (SYRE)?

As of 07 Aug 2025, Spyre Therapeutics (SYRE) is trading at a price of 15.24, with a previous close of 15.96. The stock has fluctuated within a day range of 14.94 to 15.90, while its 52-week range spans from 10.91 to 40.26.
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