Humacyte, Inc., together with its subsidiaries, engages in the development and manufacture of off-the-shelf, implantable, and bioengineered human tissues for the treatment of diseases and conditions across a range of anatomic locations in multiple therapeutic areas. The company using its proprietary and scientific technology platform to engineer and manufacture human acellular vessels (HAVs) to be implanted into patient without inducing a foreign body response or leading to immune rejection. It is developing a portfolio of HAVs, which would target the vascular repair, reconstruction, and replacement market, including vascular trauma; arteriovenous access for hemodialysis; peripheral arterial disease; pediatric heart surgery; and coronary artery bypass grafting, as well as for the delivery of cellular therapy, including pancreatic islet cell transplantation to treat Type 1 diabetes. The company was founded in 2004 and is headquartered in Durham, North Carolina.
HAV Breakthrough | Humacyte's human acellular vessels show promise in vascular treatments, offering potential solutions for trauma, hemodialysis, and peripheral artery disease |
Mixed Clinical Results | Phase 3 study reveals superior efficacy in difficult-to-treat populations, but higher thrombosis rates raise safety concerns for widespread adoption |
Market Potential | Analysts project over $1 billion in annual revenues by 2032, with price targets ranging from $6 to $25, suggesting significant upside from current $3.80 |
Regulatory Horizon | Approaching PDUFA date for HAV in vascular trauma, management confident in potential FDA approval without additional inspections or Advisory Committee meetings |
Metrics to compare | HUMA | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipHUMAPeersSector | |
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P/E Ratio | −4.9x | −0.5x | −0.5x | |
PEG Ratio | −0.13 | −0.01 | 0.00 | |
Price/Book | 10.9x | 2.0x | 2.6x | |
Price / LTM Sales | 760.6x | 3.9x | 3.2x | |
Upside (Analyst Target) | 162.6% | 240.3% | 41.6% | |
Fair Value Upside | Unlock | 27.2% | 6.0% | Unlock |