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Tango Therapeutics, Inc., a precision oncology company, focuses on the discovery and development of drugs in defined patient populations with unmet medical need. The company develops methylthioadenosine -cooperative protein arginine methyltransferase 5 (PRMT5) inhibitors, including TNG462, which is in Phase 1/2 clinical trial for treating pancreatic and lung cancer; and TNG456, a brain-penetrant PRMT5 inhibitor for the treatment of glioblastoma. It is developing TNG260, a co-repressor of repressor element-1 silencing transcription inhibitor to reverse the immune evasion effect of serine-threonine kinase 11 loss-of-function mutations for treating lung cancer. The company was founded in 2017 and is headquartered in Boston, Massachusetts.
Name | Age | Since | Title |
---|---|---|---|
Carole L. Nuechterlein | 59 | 2020 | Independent Director |
Aaron I. Davis | 43 | 2020 | Chairman & CEO |
James G. Christensen | 53 | 2020 | Independent Director |
Charles M. Baum | 63 | 2020 | Independent Director |
Christopher Fuglesang | 52 | 2020 | President & Director |
Richard A. Heyman | 64 | - | Independent Director |
James B. Avery | 58 | 2020 | Independent Director |
Barbara L. Weber | 66 | 2017 | President, CEO & Director |
Alexis A. Borisy | 53 | 2017 | Independent Chairman |
Kanishka Ram Pothula | - | 2023 | Director |
Malte Peters | 61 | 2018 | Independent Director |
Mace L. Rothenberg | 66 | 2021 | Independent Director |
Lesley Ann Calhoun | 57 | 2021 | Independent Director |
Alan Ashworth | 63 | 2021 | Founder & Member of Scientific Advisory Board |
William G. Kaelin | 67 | 2021 | Founder & Member of Scientific Advisory Board |
Antoni Ribas | 58 | 2021 | Founder & Member of Scientific Advisory Board |
Alan Huang | 52 | 2018 | Member of Scientific Advisory Board |
Ulrich Elling | - | 2021 | Member of Scientific Advisory Board |
John G. Doench | - | 2021 | Member of Scientific Advisory Board |
John Ketchum | 69 | 2023 | Independent Director |
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