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C4 Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops novel therapeutic candidates to degrade disease-causing proteins. Its lead product candidate is Cemsidomide, an orally bioavailable MonoDAC degrader of protein that is in Phase 1/2 clinical trials targeting IKZF1 and IKZF3 for multiple myeloma and non-Hodgkin lymphomas, including peripheral T-cell lymphoma and mantle cell lymphoma. The company is also developing CFT1946, an orally bioavailable BiDAC degrader targeting BRAF V600 mutant that is in Phase 1/2 clinical trials to treat melanoma, colorectal cancer, and other solid malignancies; and CFT8919, an orally bioavailable, allosteric, and mutant-selective BiDAC degrader of epidermal growth factor receptor with an L858R mutation in non-small cell lung cancer. It has strategic collaborations with F. Hoffmann-La Roche Ltd and Hoffmann-La Roche Inc.; Biogen MA, Inc.; Betta Pharmaceuticals, Co., Ltd.; Merck KGaA; and Merck Sharp & Dohme, LLC, as well as Calico Life Sciences LLC. The company was incorporated in 2015 and is headquartered in Watertown, Massachusetts.
Promising Pipeline | Explore C4 Therapeutics' lead candidate CFT1946, a BRAF V600X degrader showing superior efficacy in preclinical studies and early clinical trials |
Clinical Progress | Delve into early clinical data revealing encouraging anti-tumor activity and favorable safety profile of CFT1946 compared to historical benchmarks |
Market Potential | Learn how CFT1946's unique mechanism and safety profile could position it as a preferred treatment across various BRAF V600 mutant-driven cancers |
Analyst Outlook | BMO Capital Markets rates C4 Therapeutics as Outperform with a $20 price target, suggesting significant upside potential from current levels |
Metrics to compare | CCCC | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipCCCCPeersSector | |
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P/E Ratio | −1.6x | −2.0x | −0.5x | |
PEG Ratio | −0.05 | −0.11 | 0.00 | |
Price/Book | 0.8x | 0.9x | 2.6x | |
Price / LTM Sales | 4.1x | 23.3x | 3.2x | |
Upside (Analyst Target) | 189.3% | 153.2% | 40.5% | |
Fair Value Upside | Unlock | 16.6% | 4.4% | Unlock |