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IO Biotech, Inc., a clinical-stage biopharmaceutical company, develops immune-modulating therapeutic cancer vaccines based on the T-win technology platform. The company’s lead therapeutic cancer vaccine candidate includes IO102-IO103, which targets cancer cells and immune-suppressive cells in the tumor microenvironment that express indoleamine 2,3-dehydrogenase (IDO), and programmed death-ligand (PD-L1) that is in phase 3 clinical trial to treat melanoma, as well as in phase 2 clinical trial to treat lung, head and neck, and melanoma cancer. It also develops IO112, a product candidate that contains a single Arginase 1-derived peptide to target T cells that recognize epitopes derived from Arginase 1, which is an immunoregulatory enzyme highly expressed in difficult-to-treat tumors associated with high levels of myeloid-derived suppressor cells, including renal cell carcinoma, head and neck, breast, pancreatic, ovarian, colorectal, and prostate cancers. In addition, the company develops IO170, a TGFß1 vaccine for the treatment of solid tumors. IO Biotech, Inc. was incorporated in 2014 and is based in Copenhagen, Denmark.
Name | Age | Since | Title |
---|---|---|---|
Christian E. Elling | 55 | 2015 | Independent Director |
K. Peter Hirth | 72 | 2016 | Independent Chairman |
David V. Smith | 64 | 2022 | Independent Director |
Mai-Britt Zocca | 57 | 2015 | Founder, President, CEO, Principal Financial Officer & Director |
Heidi Hunter | 66 | 2023 | Independent Director |
Kathleen Sereda Glaub | 70 | 2018 | Independent Director |
Kapil Dhingra | 65 | - | Strategic Advisory Board Member |
Mads Hald Andersen | - | - | Co-Founder & Scientific Advisor |
Helen Louise Collins | 61 | 2023 | Independent Director |
Inge Marie Svane | - | - | Founder & Clinical Advisor |
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