IO Biotech, Inc., a clinical-stage biopharmaceutical company, develops immune-modulating therapeutic cancer vaccines based on the T-win technology platform. The company’s lead therapeutic cancer vaccine candidate includes IO102-IO103, which targets cancer cells and immune-suppressive cells in the tumor microenvironment that express indoleamine 2,3-dehydrogenase (IDO), and programmed death-ligand (PD-L1) that is in phase 3 clinical trial to treat melanoma, as well as in phase 2 clinical trial to treat lung, head and neck, and melanoma cancer. It also develops IO112, a product candidate that contains a single Arginase 1-derived peptide to target T cells that recognize epitopes derived from Arginase 1, which is an immunoregulatory enzyme highly expressed in difficult-to-treat tumors associated with high levels of myeloid-derived suppressor cells, including renal cell carcinoma, head and neck, breast, pancreatic, ovarian, colorectal, and prostate cancers. In addition, the company develops IO170, a TGFß1 vaccine for the treatment of solid tumors. IO Biotech, Inc. was incorporated in 2014 and is based in Copenhagen, Denmark.
Metrics to compare | IOBT | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipIOBTPeersSector | |
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P/E Ratio | −1.1x | −2.1x | −0.6x | |
PEG Ratio | 0.10 | 0.00 | 0.00 | |
Price/Book | 72.0x | 2.6x | 2.6x | |
Price / LTM Sales | - | 7.4x | 3.3x | |
Upside (Analyst Target) | - | 196.9% | 38.0% | |
Fair Value Upside | Unlock | −2.8% | 4.4% | Unlock |