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MeiraGTx Holdings plc, a clinical stage genetics medicines company, focusing on developing treatments for patients with serious diseases. The company develops various therapies for ocular diseases, including inherited retinal diseases and large degenerative ocular diseases; neurodegenerative diseases; and xerostomia. It is also developing AAV-AQP1 in Phase 2 trial for radiation-induced grade 2/3 radiation-induced xerostomia, as well as in Phase ½ trial for Sjogren’s syndrome; AAV-GAD in Phase 2 trial for Parkinson’s disease; AAV-RPE65 in Phase 2 trial for RPE65-associated retinal dystrophy; and AAV-CNGB3 and AAV-CNGA3, which are both in Phase 2 trial for achromatopsia, as well as offers AAV-AIPL1 for Leber congenital amaurosis (LCA) 4. In addition, the company’s products under preclinical development include AAV-RDH12 for retinol dehydrogenase 12 mutation-associated retinal dystrophy; AAV-BBS10 for Bardet-Biedl syndrome (BBS) due to BBS10 mutations; AAV-RetGC for LCA type 1; and AAV-UPF1 for amyotrophic lateral sclerosis, as well as programs for Alzheimer’s disease, and wet and dry neovascular age related macular degeneration. Further, it provides riboswitch platform for the delivery of metabolic peptides; and cell therapies for oncology, autoimmune disease, and long term intractable pain. The company has collaborations with Johnson & Johnson Innovative Medicine for the research, development, and commercialization of gene therapies for the treatment of inherited retinal disease; and Hologen Limited for the research, development, manufacture, and commercialization of AAV-GAD investigational gene therapy for the treatment of Parkinson’s disease, AAV-BDNF investigational gene therapy for genetic obesity disorders, and other genetic medicines to the central nervous system. MeiraGTx Holdings plc was founded in 2015 and is based in New York, New York.
Gene Therapy Pionee | MeiraGTx's diverse pipeline spans treatments for xerostomia, X-linked retinitis pigmentosa, and Parkinson's disease, positioning it as a leader in gene therapy innovation |
Financial Fortification | Explore how MeiraGTx secured $50 million in equity financing, including a significant $30 million investment from pharmaceutical giant Sanofi, bolstering its research capabilities |
Regulatory Milestones | Learn about MeiraGTx's crucial FDA alignment for its xerostomia treatment, potentially supporting a Biologics License Application by 2026 and accelerating market entry |
Market Valuation | Analyst price targets range from $11 to $36, suggesting significant upside potential despite the stock's current "Speculative Risk" qualifier and recent price target adjustment |
Metrics to compare | MGTX | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipMGTXPeersSector | |
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P/E Ratio | −3.7x | −1.1x | −0.5x | |
PEG Ratio | 0.05 | −0.06 | 0.00 | |
Price/Book | 18.5x | 2.2x | 2.6x | |
Price / LTM Sales | 17.7x | 9.2x | 3.3x | |
Upside (Analyst Target) | 233.3% | 307.6% | 43.5% | |
Fair Value Upside | Unlock | 18.5% | 6.9% | Unlock |