Avidity Biosciences, Inc., a biopharmaceutical company, engages in the delivery of RNA therapeutics called antibody oligonucleotide conjugates (AOCs). Its AOC platform is designed to combine the specificity of monoclonal antibodies with the precision of RNA therapeutics to target the root cause of diseases previously untreatable with such therapeutics. The company’s pipeline has three programs in registrational clinical trials, such as Delpacibart etedesiran, which is in Phase 3 development stage for the treatment of people with myotonic dystrophy type 1; Delpacibart braxlosiran that is in Phase 1/2 development stage for treating facioscapulohumeral muscular dystrophy; and Delpacibart zotadirsen, which is in the Phase 2 EXPLORE44 open-label extension study for the treatment of Duchenne muscular dystrophy. The company is also developing precision cardiology candidates targeting rare genetic cardiomyopathies, including AOC 1086 for phospholamban cardiomyopathy and AOC 1072 for protein kinase AMP-activated non-catalytic subunit gamma 2 syndrome. Avidity Biosciences, Inc. was incorporated in 2012 and is headquartered in San Diego, California.
Innovative Therapy | Avidity Biosciences leads in developing targeted RNA therapies for rare muscle diseases, utilizing its proprietary Antibody Oligonucleotide Conjugate platform |
Pipeline Progress | Explore Avidity's three lead programs for DMD, DM1, and FSHD, with potential Biologics License Applications expected between late 2025 and late 2026 |
Market Opportunity | Delve into the substantial market potential for Avidity's therapies, with the FSHD market alone estimated at $4-5 billion and DMD Exon 44 projected at $400 million in U.S. sales |
Financial Outlook | Learn about Avidity's strong financial position with $1.4 billion in cash, providing runway into mid-2027, and analyst price targets ranging from $59 to $96 |
Metrics to compare | RNA | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipRNAPeersSector | |
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P/E Ratio | −13.3x | −2.9x | −0.5x | |
PEG Ratio | 0.61 | 0.02 | 0.00 | |
Price/Book | 5.1x | 1.7x | 2.6x | |
Price / LTM Sales | 563.2x | 5.3x | 3.3x | |
Upside (Analyst Target) | 41.3% | 167.5% | 38.7% | |
Fair Value Upside | Unlock | 1.9% | 5.0% | Unlock |