Foghorn Therapeutics Inc., a clinical-stage biopharmaceutical company, engages in the discovery and development of medicines targeting genetically determined dependencies within the chromatin regulatory system in the United States. The company uses its proprietary Gene Traffic Control platform to identify, validate, and potentially drug targets within the system. It is also developing therapies for mutant cancers, such as androgen receptor, positive prostate cancer, bladder cancer, Non-Small Cell Lung (NSCLC), as well as various lymphomas and leukemias; melanoma, endometrial, gastric, breast, colorectal, and pancreatic cancers; and dependent cancers, including prostate cancer and diffuse large b-cell lymphoma. The company has collaboration agreement with Eli Lilly and Company for developing FHD-909, a selective ATPase inhibitor of BRM. Foghorn Therapeutics Inc. was incorporated in 2015 and is headquartered in Cambridge, Massachusetts.
Chromatin Pionee | Foghorn Therapeutics leads in chromatin biology, targeting cancer through gene expression regulation with innovative BAF complex-focused pipeline |
Pipeline Potential | FHD-286 and FHD-909 programs show promise in AML and BRG1 loss-of-function cancers, with crucial data releases anticipated in Q4 2024 |
Eli Lilly Backing | $300 million upfront payment from Eli Lilly partnership validates Foghorn's technology and provides substantial financial resources for development |
Market Outlook | Analyst targets range from $9 to $20, with a strong buy consensus. Total addressable market estimated in tens of billions, despite current volatility |
Metrics to compare | FHTX | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipFHTXPeersSector | |
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P/E Ratio | −3.4x | −0.4x | −0.5x | |
PEG Ratio | −0.10 | −0.01 | 0.00 | |
Price/Book | −3.4x | 2.7x | 2.6x | |
Price / LTM Sales | 10.7x | 8.7x | 3.3x | |
Upside (Analyst Target) | 130.9% | 318.4% | 43.4% | |
Fair Value Upside | Unlock | 7.1% | 7.1% | Unlock |