Wave Life Sciences Ltd., a clinical-stage biotechnology company, designs, develops, and commercializes ribonucleic acid (RNA) medicines through PRISM, a discovery and drug development platform. The company’s RNA medicines platform, PRISM, combines multiple modalities, chemistry innovation, and deep insights into human genetics to deliver scientific breakthroughs that treat both rare and prevalent disorders. It is developing WVE-006, an RNA editing oligonucleotide for the treatment of alpha-1 antitrypsin deficiency; WVE-007, a GalNAc-conjugated small interfering RNA designed to silence INHBE mRNA targeting obesity; WVE-N531, an exon skipping oligonucleotide for the treatment of Duchenne muscular dystrophy; and WVE-003, an allele-selective oligonucleotide for the treatment of Huntington’s disease (HD). The company has collaboration agreements with GlaxoSmithKline for the research, development, and commercialization of oligonucleotide therapeutics; Takeda Pharmaceutical Company Limited for the research, development, and commercialization of oligonucleotide therapeutics for disorders of the Central Nervous System; and Asuragen, Inc. for the development and potential commercialization of companion diagnostics for investigational allele-selective therapeutic programs targeting HD. Wave Life Sciences Ltd. was incorporated in 2012 and is based in Singapore.
RNA Editing Pionee | Wave Life Sciences leads in RNA-based therapeutics, with a proprietary editing platform showing promise in early human trials for genetic disorders |
AATD Breakthrough | Explore WVE-006's success in alpha-1 antitrypsin deficiency, demonstrating significant AAT level increases and validating RNA editing's potential |
Diverse Pipeline | From DMD to obesity, Wave's expansive portfolio showcases the versatility of its RNA editing technology across multiple high-value indications |
Market Outlook | Analyst price targets range from $9 to $36, reflecting the potential and risks in Wave's innovative approach to genetic medicine |
Metrics to compare | WVE | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipWVEPeersSector | |
---|---|---|---|---|
P/E Ratio | −10.0x | 2.0x | −0.5x | |
PEG Ratio | 0.30 | 0.06 | 0.00 | |
Price/Book | 9.3x | 1.5x | 2.6x | |
Price / LTM Sales | 13.8x | 3.0x | 3.3x | |
Upside (Analyst Target) | 139.8% | 71.1% | 43.4% | |
Fair Value Upside | Unlock | 9.8% | 7.1% | Unlock |