Iovance Biotherapeutics, Inc., a commercial-stage biopharmaceutical company, develops and commercializes cell therapies using autologous tumor infiltrating lymphocyte for the treatment of metastatic melanoma and other solid tumor cancers in the United States. The company offers Amtagvi, a tumor-derived autologous T cell immunotherapy used to treat adult patients with unresectable or metastatic melanoma; and Proleukin, an interleukin-2 product for the treatment of patients with metastatic melanoma and metastatic renal cell carcinoma. It develops lifileucel for treatment of melanoma, cervical cancer, non-small cell lung cancer (NSCLC), endometrial cancer, and head and neck squamous cell carcinoma; IOV-2001 to treat chronic lymphocytic leukemia and small lymphocytic lymphoma; IOV-4001 for the treatment of melanoma and NSCLC; and IOV-3001, an antibody cytokine engrafted protein for use in the TIL therapy treatment regimen. The company has collaborations and licensing agreements with WuXi Advanced Therapies, Inc.; National Institutes of Health; the National Cancer Institute; H. Lee Moffitt Cancer Center; The University of Texas M.D. Anderson Cancer Center; Cellectis S.A.; Novartis Pharma AG; and Boehringer Ingelheim Biopharmaceuticals GmbH. The company was formerly known as Lion Biotechnologies, Inc. and changed its name to Iovance Biotherapeutics, Inc. in June 2017. Iovance Biotherapeutics, Inc. was incorporated in 2007 and is headquartered in San Carlos, California.
TIL Therapy Promise | Explore Iovance's tumor-infiltrating lymphocyte technology, showing potential in advanced melanoma treatment with durable responses and survival benefits |
Financial Hurdles | Iovance faces significant cash burn and revenue challenges, with a recent guidance reset impacting stock performance and analyst projections |
Commercial Rollout | Delve into Iovance's efforts to expand its treatment center network and overcome physician hesitancy in adopting Amtagvi for earlier-stage patients |
Future Prospects | Analysts maintain cautious optimism with price targets ranging from $4 to $20, hinging on ongoing trials and potential expansion into new indications |
Metrics to compare | IOVA | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipIOVAPeersSector | |
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P/E Ratio | −2.6x | −2.7x | −0.5x | |
PEG Ratio | −0.08 | 0.01 | 0.00 | |
Price/Book | 1.3x | 1.1x | 2.6x | |
Price / LTM Sales | 4.6x | 15.3x | 3.2x | |
Upside (Analyst Target) | 156.8% | 367.3% | 41.2% | |
Fair Value Upside | Unlock | 27.6% | 6.2% | Unlock |