Revolution Medicines, Inc., a clinical-stage precision oncology company, develops novel targeted therapies for RAS-addicted cancers. The company’s research and development pipeline consist of RAS(ON) inhibitors that binds RAS variants to be used as monotherapy in combination with other RAS(ON) inhibitors and/or in combination with RAS companion inhibitors or other therapeutic agents, and RAS companion inhibitors to suppress cooperating targets and pathways that sustain RAS-addicted cancers. Its RAS(ON) inhibitors include daraxonrasib (RMC-6236), elironrasib G12C (RMC-6291), and zoldonrasib G12D (RMC-9805), which are in phase 1 clinical trial; and development candidates comprise RMC-5127 (G12V), RMC-0708 (Q61H), and RMC-8839 (G13C). The company’s RAS companion inhibitors include RMC-4630 that is in phase 2 clinical trial; RMC-5552, a selective inhibitor of mTORC1 signaling in tumors, which is in phase 1 clinical trial; and RMC-5845 that targets SOS1. Revolution Medicines, Inc. was incorporated in 2014 and is headquartered in Redwood City, California.
RAS Inhibitor Pionee | Revolution Medicines leads in RAS-dependent cancer therapies, with promising candidates like RMC-6236 and RMC-9805 showing potential in PDAC and NSCLC treatments |
Clinical Milestones | Upcoming Phase 1 trials for PDAC and NSCLC in 2024-2025 could significantly impact the company's market position and validate its innovative approach |
Financial Health | Despite operating losses, RVMD maintains a strong cash position. Analyst price targets range from $60 to $87, reflecting optimism about future prospects |
Market Opportunities | Revolution Medicines' focus on unmet needs in cancer treatment and potential for combination therapies could drive growth in the competitive oncology market |
Metrics to compare | RVMD | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipRVMDPeersSector | |
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P/E Ratio | −8.1x | −4.0x | −0.5x | |
PEG Ratio | 0.30 | −0.01 | 0.00 | |
Price/Book | 3.5x | 2.5x | 2.6x | |
Price / LTM Sales | - | 150.6x | 3.3x | |
Upside (Analyst Target) | 108.2% | 196.4% | 43.5% | |
Fair Value Upside | Unlock | 6.5% | 6.8% | Unlock |