Arcus Biosciences, Inc., a clinical-stage biopharmaceutical company, develops and commercializes cancer therapies in the United States. The company’s development product portfolio includes Casdatifan, a HIF-2a inhibitor for the treatment of kidney cancer; and Domvanalimab, an anti-TIGIT antibody, which is in Phase 2 and Phase 3 clinical trial for lung and gastrointestinal cancers. It also develops Quemliclustat, a small molecule inhibitor that targets the CD73 enzyme in the ATP-adenosine pathway, which is in phase 3 and phase 1/1b clinical trial for lung and pancreatic cancer; Etrumadenant, a dual A2a/A2b adenosine receptor antagonist, which is in phase 2 clinical trial for colorectal cancer; and Zimberelimab, an anti-PD-1 antibody. In addition, the company develops AB598, a CD39 antibody, which is in phase 1/1b clinical study for gastrointestinal cancer; and AB801, an AXL inhibitor, which is in Phase 1b clinical trial for lung cancer. It has clinical collaboration with AstraZeneca for the Phase 3 PACIFIC-8 trial evaluating domvanalimab and durvalumab in Stage 3 NSCLC and for a Phase 1/1b study evaluating casdatifan and volrustomig in IO-naive patients with ccRCC; and BVF Partners L.P. to support the discovery and development of compounds for the treatment of inflammatory diseases. Arcus Biosciences, Inc. was incorporated in 2015 and is based in Hayward, California.
Promising Pipeline | Explore Arcus Biosciences' lead candidate casdatifan, showing potential in renal cell carcinoma trials with a 46% objective response rate in combination therapy |
Financial Outlook | Delve into Arcus's financial position, with analysts forecasting further earnings decline but stock potentially undervalued with price targets ranging from $12 to $46 |
Market Positioning | Learn how Arcus's HIF-2alpha inhibitor casdatifan competes against established players, potentially offering improved efficacy in the oncology landscape |
Future Catalysts | Discover key upcoming events for Arcus, including data presentations and trial updates, with analysts assigning a 70% likelihood to positive outcomes |
Metrics to compare | RCUS | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipRCUSPeersSector | |
---|---|---|---|---|
P/E Ratio | −2.6x | −1.1x | −0.5x | |
PEG Ratio | 0.06 | −0.06 | 0.00 | |
Price/Book | 1.9x | 2.3x | 2.6x | |
Price / LTM Sales | 7.2x | 9.9x | 3.3x | |
Upside (Analyst Target) | 172.3% | 302.0% | 42.8% | |
Fair Value Upside | Unlock | 22.7% | 6.5% | Unlock |