Replimune Group, Inc., a clinical-stage biotechnology company, focuses on the development and commercialization of oncolytic immunotherapies to treat cancer. The company’s proprietary oncolytic immunotherapy product candidates are designed and intended to activate the immune system against cancer. Its lead product candidate is RP1, a selectively replicating version of HSV-1 that expresses GALV-GP R(-) and human GM-CSF for a range of solid tumors. The company is also developing RP2 that express an anti-CTLA-4 antibody-like protein to block the inhibition of the immune response otherwise caused by CTLA-4; and RP3, which express immune-activating proteins that stimulate T cells. Replimune Group, Inc. was founded in 2015 and is headquartered in Woburn, Massachusetts.
FDA Setback | Replimune faces regulatory hurdles as FDA issues Complete Response Letter for RP1, impacting near-term prospects and pipeline development |
Financial Outlook | Negative EPS projections and $397.3M market cap reflect challenges, yet cash runway suggests stability amid ongoing clinical trials |
Oncology Potential | Explore Replimune's diverse pipeline beyond RP1, including RP2 and expanded indications in skin cancers and organ transplants |
Market Valuation | Analyst targets range from $3 to $17, with recent downgrades reflecting regulatory uncertainty and potential for future growth |
Metrics to compare | REPL | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipREPLPeersSector | |
---|---|---|---|---|
P/E Ratio | −1.3x | −4.4x | −0.7x | |
PEG Ratio | 0.11 | 0.12 | 0.00 | |
Price/Book | 1.1x | 7.6x | 2.6x | |
Price / LTM Sales | - | 80.2x | 3.4x | |
Upside (Analyst Target) | −26.0% | 205.8% | 36.2% | |
Fair Value Upside | Unlock | −0.5% | 4.1% | Unlock |