SpringWorks Therapeutics, Inc., a commercial-stage biopharmaceutical company, engages in the development and commercialization of medicines for underserved patient populations suffering from rare diseases and cancer. It offers OGSIVEO (nirogacestat), an oral small molecule gamma secretase inhibitor for the treatment of desmoid tumors; and GOMEKLI (mirdametinib), an oral small molecule inhibitor of MEK1 and MEK2 for the treatment of adult and pediatric patients two years of age and older with neurofibromatosis type 1-associated plexiform neurofibromas (NF1-PN). The company also develops Nirogacestat, is also in Phase 2 clinical development as a monotherapy for the treatment of ovarian granulosa cell tumors (GCT), a subtype of ovarian cancer; and mirdametinib for the treatment of solid tumors harboring other MAPK aberrations, including for the treatment of pediatric and young adult patients with low-grade gliomas that is in Phase 1/2 clinical trial. In addition, its products under development include Brimarafenib (BGB-3245), an oral selective small molecule inhibitor of monomeric and dimeric forms of activating BRAF mutations. The company has license agreements with Pfizer Inc. for nirogacestat and mirdametinib; and Katholieke Universiteit Leuven and the Flanders Institute for Biotechnology for a portfolio of novel small molecule inhibitors of the TEA Domain. SpringWorks Therapeutics, Inc. was founded in 2017 and is headquartered in Stamford, Connecticut. As of July 1, 2025, SpringWorks Therapeutics, Inc. operates as a subsidiary of Merck KGaA.
Acquisition Impact | Explore how Merck KGaA's $3.9 billion acquisition of SpringWorks Therapeutics could reshape the company's future and accelerate its growth in rare diseases |
Pipeline Potential | Delve into SpringWorks' promising therapies, including Ogsiveo and Gomekli, and their market opportunities in desmoid tumors and neurofibromatosis |
Financial Outlook | Analysts project continued negative earnings despite strong sales growth, with EPS estimates ranging from -$3.26 to -$1.94 for upcoming fiscal years |
Market Positioning | Learn how SpringWorks navigates the competitive biotech landscape, awaits EU regulatory decisions, and leverages its expertise in rare diseases and oncology |
Metrics to compare | SWTX | Peers Peers - average of corresponding metrics from companies closely matching SWTX: | Sector Sector - Average of metrics from a broad group of related Healthcare sector companies | Relationship RelationshipSWTXPeersSector |
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P/E Ratio | −13.9x | 0.0x | −0.5x | |
PEG Ratio | −0.42 | 0.00 | 0.00 | |
Price/Book | 8.5x | 0.0x | 2.6x | |
Price / LTM Sales | 16.1x | 0.0x | 3.3x | |
Upside (Analyst Target) | 0.0% | 0.0% | 43.5% | |
Fair Value Upside | Unlock | 0.0% | 6.3% | Unlock |